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Indian J Exp Biol ; 2000 Jul; 38(7): 727-9
Article in English | IMSEAR | ID: sea-60497

ABSTRACT

HA-1-92, a new oxohexaene polyene macrolide showed significant hypolipidemic and hypoprostatic activity both in rat and rabbit models. HA-1-92 did not elicit significant effect on blood pressure or respiration in anaesthetized rat or on various isolated tissue preparation studies.


Subject(s)
Animals , Anti-Bacterial Agents/pharmacology , Hypolipidemic Agents/pharmacology , Lipids/blood , Macrolides , Male , Organ Size/drug effects , Prostate/anatomy & histology , Rabbits , Rats , Rats, Wistar
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